GSK-5959

• Description:

  GSK-5959 exhibits >100-fold selectivity for BRPF1 (IC50= 80 nM) over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains. Inhibits BRPF1 interaction with histone H3.3, which is involved in the epigenetic regulation of gene expression and have been implicated in human cancer.

• Format:

  Solid

• Molecular Formula:

  C22H26N4O3

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  At least 6 months at -20°C.

• Calculated Molecular Weight:

  394.5 Da

• CAS Number:

  901245-65-6