ω-Conotoxin-GVIA

• Description:

  ω-conotoxin-GVIA (omega conotoxin GVIA) is a conotoxin thath has been isolated from the venom of the cone Conus geographus. ω-conotoxin GVIA acts at presynaptic membranes. It binds and blocks specifically voltage-dependent N-type Ca2+channels Cav2.2 channel with an ED50 of 68pM.

• Specifications:

  Selective blocker of Cav2.2 channel

• Target:

  Ca channels

• Sequence:

  CKS (Hyp) GSSCS (Hyp) TSYNCCRSCN (Hyp) YTKRCY

• Peptide Number:

  08CON003

• Disulfide Bonds:

  Cys1-Cys16; Cys8-Cys19; Cys15-Cys26

• N Terminal Sequence:

  H

• C Terminal Sequence:

  NH2

• CAS Number:

  106375-28-4