α-conotoxin-GI

• Description:

  α-conotoxin GI (alpha-conotoxin GI) is a conopeptide that has been isolated from the venom of the cone snail Conus geographus. α-conotoxin GI is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin MI or d-Turbocurarine. α-conotoxin GI allows to distinguish between the two agonist sites as it binds 10,000-fold more tightly to the α/δ than to the α/γ site excepted in Torpedo which is the reverse.

• Specifications:

  α/δ site of the muscle-type nAChR blocker

• Target:

  Acetylcholine receptors

• Sequence:

  ECCNPACGRHYSC

• Peptide Number:

  08CON015

• Disulfide Bonds:

  Cys2-Cys7; Cys3-Cys13

• N Terminal Sequence:

  H

• C Terminal Sequence:

  NH2

• CAS Number:

  76862-65-2