α-conotoxin-GI

CAT: 0466-08CON015-01000Size: 1 mgDry Ice: NoHazardous: No
CAT#:0466-08CON015-01000Size:1 mg
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Description
α-conotoxin GI (alpha-conotoxin GI) is a conopeptide that has been isolated from the venom of the cone snail Conus geographus. α-conotoxin GI is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin MI or d-Turbocurarine. α-conotoxin GI allows to distinguish between the two agonist sites as it binds 10,000-fold more tightly to the α/δ than to the α/γ site excepted in Torpedo which is the reverse.
CAS Number
76862-65-2
Specifications
α/δ site of the muscle-type nAChR blocker
Target
Acetylcholine receptors
Sequence
ECCNPACGRHYSC
Peptide Number
08CON015
Disulfide Bonds
Cys2-Cys7; Cys3-Cys13
N Terminal Sequence
H
C Terminal Sequence
NH2

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