Phlotoxin-1

• Description:

  Phlotoxin-1 is a new member of the NaSpTx-1 family. Phlotoxin-1 has been purified originally from the venom of Phlogiellus sp., Theraphosidae Selenocosmiinae (endemic to Papua New Guinea) . Phlotoxin-1 inhibits Nav1.7 with an IC50 value of 39 ± 2 nM.

• Specifications:

  Blocker of Nav1.7 channel

• Target:

  Na channels

• Sequence:

  ACLGQWDSCDPKASKCCPNYACEWKYPWCRYKLF

• Peptide Number:

  PHX001

• Disulfide Bonds:

  Cys1-Cys4; Cys2-Cys5; Cys3-Cys6

• N Terminal Sequence:

  H

• C Terminal Sequence:

  OH