Kaliotoxin-1

• Description :

  Kaliotoxin-1 (KTX1) has been isolated from the venom of the Scorpion Androctonus mauretanicus mauretanicus. Kaliotoxin-1 shows a high structural affinity with Iberiotoxin and Charybdotoxin that inhibit KCa2+ channels activity. According to several studies, it appears that Kaliotoxin-1 has a weak inhibitory effect on KCa2+ channels, but it is a potent and selective inhibitor of voltage-activated potassium channel (Kv1.1, Kv1.2, Kv1.3) .

• Specifications :

  Blocker of potassium channels

• Target :

  K channels

• Sequence :

  GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK

• Peptide Number :

  08KTX002

• Disulfide Bonds :

  Cys8-Cys28; Cys14-Cys33; Cys18-Cys35

• N Terminal Sequence :

  H

• C Terminal Sequence :

  OH