Kaliotoxin-1

• Description:

  Kaliotoxin-1 (KTX1) has been isolated from the venom of the Scorpion Androctonus mauretanicus mauretanicus. Kaliotoxin-1 shows a high structural affinity with Iberiotoxin and Charybdotoxin that inhibit KCa2+ channels activity. According to several studies, it appears that Kaliotoxin-1 has a weak inhibitory effect on KCa2+ channels, but it is a potent and selective inhibitor of voltage-activated potassium channel (Kv1.1, Kv1.2, Kv1.3) .

• Specifications:

  Blocker of potassium channels

• Target:

  K channels

• Sequence:

  GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK

• Peptide Number:

  08KTX002

• Disulfide Bonds:

  Cys8-Cys28; Cys14-Cys33; Cys18-Cys35

• N Terminal Sequence:

  H

• C Terminal Sequence:

  OH