Echistatin α1 isoform

• Description :

  Echistatin was originally purified from the venom of the viper Echis carinatus. Echistatin is a cyclic RGD peptide that inhibits platelet aggregation by inhibiting the glycoprotein IIb/IIIa complex receptor. Echistatin is a potent disintegrin that antagonize αVβ3 integrin and has been described to inhibit cell proliferation, migration, invasion, and adhesion of αVβ3 expressing cells.

• Specifications :

  Antagonization of αVβ3 integrin. Inhibition of cell proliferation, migration, invasion, and adhesion of αVβ3 expressing cells.

• Target :

  Integrins

• Sequence :

  ECESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPAT

• Peptide Number :

  ECH001

• Disulfide Bonds :

  Cys2-Cys11; Cys7-Cys32; Cys8-Cys37; Cys20-Cys39

• N Terminal Sequence :

  H

• C Terminal Sequence :

  OH

• CAS Number :

  154303-05-6