Products for Research Use Only
RegisterLogin

ADWX-1

CAT: 0466-13ADW001-00100Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0466-13ADW001-00100Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ADWX-1 is an optimised synthetic analog of the scorpion peptide BmKTx. ADWX-1 is known to block voltage-gated Kv1.3 channel with a high affinity (IC50 = 1.89 pM) and selectivity (340 fold greater affinity than for voltage-dependent) . ADWX-1 inhibits CD4+ CCR7– T-cell proliferation. ADWX-1 is an interesting therapeutic candidate to treat auto-immune disorders such as multiple sclerosis, type-1 diabetes, rheumatoid arthritis and psoriasis. This peptide is a valuable tool for studying the structure-function of Kv1.3 channel and auto-immunity pathways
Specifications
Kv1.3 channel blocker
Target
K channels
Sequence
VGINVKCKHSRQCLKPCKDAGMRFGKCTNGKCHCTPK
Peptide Number
13ADW001
Disulfide Bonds
Cys7-Cys27; Cys13-Cys32; Cys17-Cys34
N Terminal Sequence
H
C Terminal Sequence
OH

Related Products

CatalogName
CRB1001037-01GLP-1 (1-37) - (Hormones)
SB127-0.5MGNERP-1 - Neuroendocrine regulatory peptide 1
SB127NERP-1 - Neuroendocrine regulatory peptide 1
SB127-1MGNERP-1 - Neuroendocrine regulatory peptide 1
PHX001-50010Phlotoxin-1
PHX001-01000Phlotoxin-1
NMB001-01000NMB-1
10LEI001-01000Leiurotoxin-1
12GSF001-01000GsAF-1
PHX001-00100Phlotoxin-1

Alternative Products

CatalogName
HY-P1409ADWX 1
PP51158ADWX-1
HY-P1409A-01ADWX 1 (TFA)
167621ADWX 1 discontinued
GTR19240624-01ADWX 1 TFA
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose

Popular Products