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CLIP (86-100)

CAT: 0804-HY-P1826-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1826-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP) . CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1].
CAS Number
648881-58-7
UNSPSC
12352209
Target
CD74
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clip-86-100.html
Purity
98.49
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=C([C@@H]1CCCN1)N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C72H128N20O19S3
Molecular Weight
1674.10
References & Citations
[1]van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3 (12) :e941737. eCollection 2014 Dec.|[2]Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162 (3) :1502-9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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