Oxeladin (citrate)

• UNSPSC Description:

  Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research[1][2].

• Target Antigen:

  Sigma Receptor

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Neurological Disease; Cardiovascular Disease; Others

• Assay Protocol:

  https://www.medchemexpress.com/Oxeladin-citrate.html

• Purity:

  98.0

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : ≥ 50 mg/mL

• Smiles:

  O=C(OCCOCCN(CC)CC)C(CC)(CC)C1=CC=CC=C1.O=C(CC(C(O)=O)(O)CC(O)=O)O

• Molecular Weight:

  527.60

• References & Citations:

  [1]Schreihofer DA, et al. Treatment of Stroke at a Delayed Timepoint with a Repurposed Drug Targeting Sigma 1 Receptors. Transl Stroke Res. 2023. Epub ahead of print.|[2]Dalwadi DA, et al. Brain-derived neurotrophic factor for high-throughput evaluation of selective Sigma-1 receptor ligands. J Pharmacol Toxicol Methods. 2022;113:107129.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  52432-72-1