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Clomiphene (citrate)

CAT: 0804-HY-B0463-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0463-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment[1][2][3].
CAS Number
50-41-9
Product Name Alternative
Clomifene citrate
UNSPSC
12352005
Hazard Statement
H361
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clomiphene-citrate.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : ≥ 50 mg/mL|H2O : 1 mg/mL (ultrasonic)
Smiles
Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(O)=O)(C(O)=O)CC(O)=O
Molecular Formula
C32H36ClNO8
Molecular Weight
598.08
Precautions
H361
References & Citations
[1]Jiann B P, et al. Effect of clomiphene on Ca2+ movement in human prostate cancer cells [J]. Life Sciences, 2002, 70 (26) : 3167-3178.|[2]London S N, et al. Clomiphene citrate-induced perturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes in vivo and in vitro [J]. Fertility and sterility, 2000, 73 (3) : 620-626.|[3]Akintoye O O, et al. Synergistic action of carvedilol and clomiphene in mitigating the behavioral phenotypes of letrozole-model of PCOS rats by modulating the NRF2/NFKB pathway [J]. Life Sciences, 2023, 324: 121737.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Biochem Biophys Res Commun. 2020 Feb 19;522 (4) :862-868.|bioRxiv. 2020 May.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.|Patent. US11696914.

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