Piperazine (citrate)

CAT: 0804-HY-17599Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17599Size:500 mg
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Description
Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist[1]. Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities[2].
CAS Number
[144-29-6]
Product Name Alternative
1,4-Diazacyclohexane (citrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Piperazine-citrate.html
Purity
98.0
Solubility
DMSO : 2.17 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CC(C(O)=O)(O)CC(O)=O)O.O=C(CC(C(O)=O)(O)CC(O)=O)O.N1CCNCC1.N2CCNCC2.N3CCNCC3
Molecular Formula
C6H8O7.3/2C4H10N2
Molecular Weight
321.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Lovell RA. Ivermectin and piperazine toxicoses in dogs and cats. Vet Clin North Am Small Anim Pract. 1990;20 (2) :453-468. |[2]Girase PS, et al. An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review. Eur J Med Chem. 2021;210:112967. |[3]Jain A, et al. Piperazine: A Promising Scaffold with Analgesic and Anti-inflammatory Potential. Drug Res (Stuttg) . 2021;71 (2) :62-72. |[4]Kumar RR, et al. Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure-Activity Relationships. ChemMedChem. 2021;16 (12) :1878-1901.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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