MA-0204

CAT: 0804-HY-114739-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-114739-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD) [1].
CAS Number
[2095128-17-7]
Product Name Alternative
GMX1778 (nicotinate), GMX1777; EB-1627
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/MA-0204.html
Purity
99.31
Solubility
DMSO : 43.33 mg/mL (ultrasonic)
Smiles
O=C(C[C@@H](CCCOC1=CC=CC=C1CN2C(C)=CN=C2C3=CC=C(C=C3)OC(F)(F)F)C)O
Molecular Formula
C25H27F3N2O4
Molecular Weight
476.49
References & Citations
[1]Lagu B, et al. Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD) . ACS Med Chem Lett. 2018 Jul 31;9 (9) :935-940.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARβ/δ

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Alternative Products

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BA4461-5MA-0204
A19031-50MA-0204 50mg
A19031-5MA-0204 5mg
A19031-10MA-0204 10mg
A19031-1MA-0204 1mg
A19031-100MA-0204 100mg
A19031-25MA-0204 25mg
A19031-200MA-0204 200mg
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