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8-MA-cAMP

CAT: 0804-HY-137530Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137530Size:1 Each
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Description
8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I[1].
CAS Number
33823-18-6
Product Name Alternative
8-Methylamino-cAMP
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-ma-camp.html
Smiles
O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C(NC)=NC4=C3N=CN=C4N
Molecular Formula
C11H15N6O6P
Molecular Weight
358.25
References & Citations
[1]Schwede, et al. 8-Substituted cAMP analogues reveal marked differences in adaptability, hydrogen bonding, and charge accommodation between homologous binding sites (AI/AII and BI/BII) in cAMP kinase I and II. Biochemistry 39.30 (2000) : 8803-8812.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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GTR19236824-018-MA-cAMP
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