KPU-300

• Description:

  KPU-300 (compound 6b) is a tubulin inhibitor. KPU-300 has potent cytotoxicity with an IC50 value of 7.0 nM against HT-29 cells[1].

• UNSPSC:

  12352005

• Target:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/kpu-300.html

• Smiles:

  O=C(/C(NC/1=O)=C/C2=CC=CC(C(C3=CC=CC=C3)=O)=C2)NC1=C/C4=NC=CC=C4

• Molecular Formula:

  C24H17N3O3

• Molecular Weight:

  395.41

• References & Citations:

  [1]Yoshiki Hayashi, et al. Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure. ACS Med Chem Lett. 2014 Jul 23;5 (10) :1094-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1620692-60-5]