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DSP 4 (free base)

CAT: 0804-HY-121602Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121602Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DSP 4 Free base is a selective neurotoxin that targets noradrenergic neurons in the locus coeruleus noradrenergic system. DSP 4 Free base possesses the unique ability to cross the blood–brain barrier. DSP 4 Free base cyclizes to form a reactive aziridinium derivative that accumulates in noradrenergic neurons.
CAS Number
62078-98-2
UNSPSC
12352101
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dsp-4-free-base.html
Smiles
ClCCN(CC)CC1=C(Br)C=CC=C1
Molecular Formula
C11H15BrClN
Molecular Weight
276.60
References & Citations
[1]Neurotoxicity of N- (2-chloroethyl) -N-ethyl-2-bromobenzylamine hydrochloride (DSP 4) on noradrenergic neurons is mimicked by its cyclic aziridinium derivative
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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