β-Amyrone

• Description :

  β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity[1][2][3][4].

• Product Name Alternative :

  β-Amyron

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  CHIKV; COX; Fungal; PPAR

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/β-amyrone.html

• Purity :

  99.87

• Solubility :

  Ethanol : 12.5 mg/mL (ultrasonic)

• Smiles :

  C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CCC(C)(C4)C)C)=CC[C@]1([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC2)C)C

• Molecular Formula :

  C30H48O

• Molecular Weight :

  424.70

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Patrícia D O de Almeida, et al. Anti-Inflammatory Activity of Triterpenes Isolated from Protium paniculatum Oil-Resins. Evid Based Complement Alternat Med. 2015;2015:293768.|[2]Mélanie Bourjot, et al. Chemical constituents of Anacolosa pervilleana and their antiviral activities. Fitoterapia. 2012 Sep;83 (6) :1076-80. |[3]Ki-Kwang Oh, et al. Elucidating Drug-Like Compounds and Potential Mechanisms of Corn Silk (Stigma Maydis) against Obesity: A Network Pharmacology Study. Curr Issues Mol Biol. 2021 Nov 6;43 (3) :1906-1936. |[4]Ata A, et al. Chemical constituents of Drypetes gossweileri and their enzyme inhibitory and anti-fungal activities. Phytochemistry Letters, 2011, 4 (1) : 34-37.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  COX-2

• CAS Number :

  [638-97-1]