Carbazomycin D

• Description:

  Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively[1].

• UNSPSC:

  12352005

• Target:

  Bacterial; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/carbazomycin-d.html

• Smiles:

  COC(C(C1=C2)=C3NC1=CC=C2OC)=C(C(C)=C3C)OC

• Molecular Formula:

  C17H19NO3

• Molecular Weight:

  285.34

• References & Citations:

  [1]Intaraudom C, et al. Antimalarial and antituberculosis substances from Streptomyces sp. BCC26924[J]. Tetrahedron, 2011, 67 (39) : 7593-7597.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [108073-63-8]