TLE 1 Recombinant Rabbit Monoclonal Antibody [JE41-40]

TLE 1 Recombinant Rabbit Monoclonal Antibody [JE41-40]

• Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity). The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
• Product Name Alternative: E (Sp1) homolog antibody Enhancer of split groucho 1 antibody Enhancer of split groucho like protein 1 antibody Enhancer of split groucho-like protein 1 antibody ESG antibody ESG1 antibody GRG1 antibody TLE1 antibody TLE1_HUMAN antibody Transducin like enhancer of split 1 (E (sp1) homolog Drosophila) antibody Transducin like enhancer of split 1 antibody Transducin like enhancer of split 1 homolog of Drosophila E (sp1) antibody Transducin like enhancer protein 1 antibody Transducin-like enhancer protein 1 antibody
• Abbreviation: TLE1
• CAS Number: 9000-83-3
• Swiss Prot: Q04724 Human, Q62440 Mouse,
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within
• Isotype: IgG
• Clone: JE41-40
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: 293T cell lysate, HepG2 cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, Human lung tissue lysate, Mouse lung tissue lysate, Rat lung tissue lysate, 293T, human colon tissue, mouse lung tissue, rat lung tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:50 ;IHC-P: 1:50
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 83 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes