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DOPE

CAT: 0804-HY-112005-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112005-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].
CAS Number
[4004-05-1]
Product Name Alternative
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-2-dioleoyl-sn-glycero-3-phosphoethanolamine.html
Purity
99.67
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O
Molecular Formula
C41H78NO8P
Molecular Weight
744.03
Precautions
H302, H315, H319, H335
References & Citations
[1]Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24 (3) :263-268.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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