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DOPG

CAT: 0804-HY-142980Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142980Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2) . Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) [1].
CAS Number
62700-69-0
Product Name Alternative
Dioleoylphosphatidylglycerol
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dioleoylphosphatidylglycerol.html
Solubility
10 mM in DMSO
Smiles
OCC(O)COP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(O)=O
Molecular Formula
C42H79O10P
Molecular Weight
775.04
References & Citations
[1]Chang L, et al. Low-dose dioleoylphosphatidylglycerol (DOPG) inhibits heat shock protein B4 (HSPB4) -induced activation of toll-like receptor 2 (TLR2) in a reporter cell line. Investigative Ophthalmology & Visual Science, 2020, 61 (7) : 357-357.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported