DOPG

• Description :

  Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2) . Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) [1].

• Product Name Alternative :

  Dioleoylphosphatidylglycerol

• UNSPSC :

  12352200

• Target :

  Liposome

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/dioleoylphosphatidylglycerol.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OCC(O)COP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(O)=O

• Molecular Formula :

  C42H79O10P

• Molecular Weight :

  775.04

• References & Citations :

  [1]Chang L, et al. Low-dose dioleoylphosphatidylglycerol (DOPG) inhibits heat shock protein B4 (HSPB4) -induced activation of toll-like receptor 2 (TLR2) in a reporter cell line. Investigative Ophthalmology & Visual Science, 2020, 61 (7) : 357-357.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [62700-69-0]