CCL17 rabbit pAb

• Background:

  This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

• Description:

  This antimicrobial gene is one of several Cys-Cys (CC) Cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The Cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],

• Synonyms:

  C-C motif chemokine 17 (CC chemokine TARC;Small-inducible cytokine A17;Thymus and activation-regulated chemokine)

• Gene ID:

  6361

• UniProt:

  Q92583

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human CCL17 AA range: 21-70

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000, ELISA (peptide) 1:5000-20000

• Molecular Weight:

  10kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  10 kD

• Subcellular Location:

  Secreted.

• Other Product Names:

  C-C motif chemokine 17 (CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine)

• Gene ID (Human):

  6361

• SwissProt (Human):

  Q92583