CCL17 rabbit pAb

CAT: 0855-ES17761-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES17761-01Size:50 µL

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Background

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

Description

This antimicrobial gene is one of several Cys-Cys (CC) Cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The Cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],

Product Name Alternative

C-C motif chemokine 17 (CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine)

UniProt

Q92583

Swiss Prot

Q92583

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human CCL17 AA range: 21-70

Target

CCL17

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, ELISA (peptide) 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

10kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

10kD

Fragment

IgG

Subcellular Location

Secreted.

Other Product Names

C-C motif chemokine 17 (CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine)

Gene ID (Human)

6361

UniProtKB · Q92583

C-C motif chemokine 17

CCL17_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q92583
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CCL17
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: A0N0Q9, Q2M287

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal

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