Citrullinated β-Catenin (human, recombinant)

• Description:

  Citrullinated β-Catenin (human, recombinant)_x000D_ Catalog number: B2017285_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 72 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’80°C_x000D_ Keywords: Catenin β-1, CTNNB1, Catenin (Cadherin-Associated Protein), β1, 88kDa, EVR7, MRD19, NEDSDV_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Qu Y, Olsen JR, Yuan X, Cheng PF, Levesque MP, Brokstad KA, Hoffman PS, Oyan AM, Zhang W, Kalland KH, Ke X. Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer Nat Chem Biol. 2018 Jan;14(1):94-101._x000D_ 2: Tsai CY, Hsieh SC, Liu CW, Lu CH, Liao HT, Chen MH, Li KJ, Wu CH, Shen CY, Kuo YM, Yu CL. The Expression of Non-Coding RNAs and Their Target Molecules in Rheumatoid Arthritis: A Molecular Basis for Rheumatoid Pathogenesis and Its Potential Clinical Applications Int J Mol Sci. 2021 May 26;22(11):5689._x000D_ 3: Zhou J, Biesterveld BE, Li Y, Wu Z, Tian Y, Williams AM, Tian S, Gao W, Bhatti UF, Duan X, Wang T, Zhang J, Jiang B, Wang Z, Alam HB. Peptidylarginine Deiminase 2 Knockout Improves Survival in hemorrhagic shock Shock. 2020 Oct;54(4):458-463._x000D_ 4: Gijon M, Metheringham RL, Toss MS, Paston SJ, Durrant LG. The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer Pathobiology. 2022;89(1):38-48._x000D_ 5: Chen DQ, Cao G, Chen H, Liu D, Su W, Yu XY, Vaziri ND, Liu XH, Bai X, Zhang L, Zhao YY. Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease Redox Biol. 2017 Aug;12:505-521._x000D_ 6: Miao CG, Huang C, Huang Y, Yang YY, He X, Zhang L, Lv XW, Jin Y, Li J. MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats Cell Signal. 2013 Mar;25(3):598-608._x000D_ 7: Bowden TJ, Kraev I, Lange S. Extracellular Vesicles and Post-Translational Protein Deimination Signatures in Mollusca-The Blue Mussel (Mytilus edulis), Soft Shell Clam (Mya arenaria), Eastern Oyster (Crassostrea virginica) and Atlantic Jacknife Clam (Ensis leei) Biology (Basel). 2020 Nov 25;9(12):416._x000D_ 8: Liu J, Xiao Q, Xiao J, Niu C, Li Y, Zhang X, Zhou Z, Shu G, Yin G. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduct Target Ther. 2022 Jan 3;7(1):3._x000D_ 9: Yu F, Yu C, Li F, Zuo Y, Wang Y, Yao L, Wu C, Wang C, Ye L. Wnt/β-catenin signaling in cancers and targeted therapies Signal Transduct Target Ther. 2021 Aug 30;6(1):307._x000D_ 10: Zhang X, Dong N, Hu X. Wnt/β-catenin Signaling Inhibitors Curr Top Med Chem. 2023;23(10):880-896. _x000D_ _x000D_ Products Related to Citrullinated β-Catenin (human, recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2017285 (100 µg)_x000D_ Citrullinated β-Catenin (human, recombinant) is a lab-produced version of the human β-Catenin protein modified by citrullination. β-Catenin regulates cell adhesion and gene transcription, part of the Wnt signaling pathway. Citrullination, a post-translational modification, converts arginine to citrulline, affecting protein function. This protein is used in research to study its role in diseases. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3