Human Fibrinogen (PAD2 Citrullinated)

• Description:

  Fibrinogen is a glycoprotein complex composed of three different polypeptides (α, β, γ) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.

• Shipping Conditions:

  Gel Pack

• Storage Conditions:

  -80°C

• Shelf Life:

  12 months