Human Fibrinogen (PAD4 Citrullinated)
CAT:
26-P1719-100
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Human Fibrinogen (PAD4 Citrullinated)
- Description: Fibrinogen is a glycoprotein complex composed of three different polypeptides (α, β, γ) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.
- Shipping Conditions: Gel Pack
- Storage Conditions: -80°C
- Shelf Life: 12 months