Anticancer agent 223

Anticancer agent 223

• CAS Number: 9007-83-4
• UNSPSC Description: Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394)-resistant A2780 cells to cisplatin (HY-17394) treatment[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/anticancer-agent-223.html
• Smiles: ClC1=CC=C(NC(C2CCN(C3=NC=NC4=C3C=CC=C4)CC2)=O)C=C1
• Molecular Weight: 366.84
• References & Citations: [1]Thuy Lu Vo T, et al. Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors. Bioorg Med Chem Lett. Published online May 15, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported