Products for Research Use Only

PROTAC CDK2/4 Degrader-1

CAT: 0013-GTR19276516-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19276516-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACCDK2/4 Degrader-1 (Compound 5) is a potent CDK2/4 PROTAC degrader with a DC50 of ≤ 10 nM for both CDK2 and CDK4. It demonstrates excellent activity in inhibiting cell proliferation in OVCAR3 and T47D cell lines. This compound is applicable for breast cancer and ovarian cancer research.
CAS Number
3108138-84-4
Smiles
O=C1NC (=O) C (C2=NN (C=3C=C (C=CC23) C4CCN (CCCS (=O) (=O) N5CCC (NC6=NC=C (OC (F) F) C=N6) CC5) CC4) C) CC1
Molecular Formula
C31H40F2N8O5S
Molecular Weight
674.77
Storage Conditions
-20°C
Notes
For research use only.