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11β-HSD1-IN-25

CAT: 0013-GTR19274985-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274985-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
11β-HSD1-IN-25 is a selective and orally bioavailable inhibitor of 11β-HSD1. It effectively reduces glucocorticoid levels in vitro and in serum, while also diminishing lipid accumulation in both in vitro and in vivo models. 11β-HSD1-IN-25 modulates lipid metabolism through a dual mechanism: inhibiting 11β-HSD1 and activating the AMP-activated protein kinase (AMPK) signaling pathway. This compound is valuable for research on obesity and related metabolic disorders in vivo.
CAS Number
1261266-23-2
Smiles
C (\C1=C (C (F) (F) F) C=CC=C1F) =C\2/C (=O) \C (=C\C3=C (C (F) (F) F) C=CC=C3F) \CC2
Molecular Formula
C21H12F8O
Molecular Weight
432.31
Storage Conditions
-20°C
Notes
For research use only.

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