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RIPK1-IN-11

CAT: 0013-GTR19185823-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185823-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RIPK1-IN-11 is a potent, orally bioavailable small molecule inhibitor of RIPK1, demonstrating high affinity (Kd = 9.2 nM) and functional inhibition (IC50 = 67 nM) . It effectively blocks necroptosis in both human and mouse cellular models and shows anti-inflammatory activity, supporting its use in research on inflammatory and neurodegenerative diseases.
CAS Number
2173557-02-1
Field of Research
Cell Biology, Signal Transduction
Smiles
N (C (=O) C1CC1) C=2SC=3C (N2) =CC=C (C3) C=4C=C (NC (OC5CCOCC5) =O) C (C) =NC4
Molecular Formula
C23H24N4O4S
Molecular Weight
452.53
Storage Conditions
-20°C
Notes
For research use only.

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