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PARP1/EZH2-IN-1

CAT: 0013-GTR19275224-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275224-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1/EZH2-IN-1 is a selective dual inhibitor targeting both PARP1 and EZH2. It exhibits IC50 values of 28 nM for PARP1, 414 nM for PARP2, and 74 nM for EZH2. This compound inhibits the proliferation and migration of TNBC cells (triple-negative breast cancer cells) . It can induce PANoptosis, a form of cell death that includes apoptosis, pyroptosis, and necroptosis, elevate reactive oxygen species (ROS) levels, and activate associated inflammatory pathways. PARP1/EZH2-IN-1 is applicable in research related to triple-negative breast cancer.
Storage Conditions
-20°C
Notes
For research use only.

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