Cbz-QFR-kbt

CAT: 0013-GTR19274074-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274074-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Cbz-QFR-kbt is a ketobenzothiazolone-based TMPRSS2 inhibitor with an IC50 of 0.42 nM. It also exhibits inhibitory activity against Matriptase, Hepsin, HGFA, and Factor Xa, with IC50 values of 1, 1.3, 85, and 85 nM, respectively. Furthermore, Cbz-QFR-kbt demonstrates significant inhibitory effects on SARS-CoV-2 and H1N1 (IC50= 60 nM) and is applicable for antiviral research.

CAS Number

3086979-57-6

Smiles

C ([C@@H] (NC ([C@H] (CC1=CC=CC=C1) NC ([C@@H] (NC (OCC2=CC=CC=C2) =O) CCC (N) =O) =O) =O) CCCNC (=N) N) (=O) C3=NC=4C (S3) =CC=CC4

Molecular Formula

C35H40N8O6S

Molecular Weight

700.82

Storage Conditions

-20°C

Notes

For research use only.

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