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UM-259

CAT: 0013-GTR19273676-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273676-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UM-259 is a STING inhibitor with an EC50 of 1.50 μM in THP1-Dual cells expressing wild-type STING. It blocks STING oligomerization and inhibits diABZI-induced phosphorylation of TBK1 and IRF3, thereby suppressing the transcription of IFNβ and IL6, and reducing IFNβ secretion. UM-259 can be used to study STING-dependent inflammation and neurological disorders.
Storage Conditions
-20°C
Notes
For research use only.

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