Products for Research Use Only
RegisterLogin

MBL-II-141

CAT: 0013-GTR19272973-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19272973-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MBL-II-141 is a potent ABCG2 inhibitor with an IC50 of 0.11 μM. It inhibits the transport function of ABCG2 in a non-competitive manner, preventing ABCG2 from expelling substrates (such as Irinotecan) out of cells, thereby increasing the intracellular accumulation of the drug. MBL-II-141 does not affect ABCB1 (P-gp) or ABCC1 (MRP1) and exhibits very low cytotoxicity (IG50 > 100 μM) . This compound is useful for studying tumor multidrug resistance (MDR) .
CAS Number
1353747-12-2
Smiles
O=C1C=C (OC2=CC=CC (OCC3=CC=C (Br) C=C3) =C12) C (=O) NCCC4=CNC=5C=CC (OC) =CC54
Molecular Formula
C28H23BrN2O5
Molecular Weight
547.41
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19234998-01MBL-IN-3
GTR19262580-01MBL-IN-4
GTR17969193Mbl Antibody
GTR17980756Mbl Antibody
GTR19261751-01MBL-IN-2
GTR19258029-01MBL-IN-5
GTR17981360Mbl Antibody
GTR19273062-01MBL-IN-6
GTR19231468-01MBL-IN-1
GTR18904026-01PT-141

Alternative Products

CatalogName
HY-17648MBL-II-141
101-M562MBL
GWB-FAA67BMBL, Antibody
T209115-01MBL-IN-2
HY-155104MBL-IN-1
T86866-01MBL-IN-3
HY-175724MBL-IN-6
HY-173472MBL-IN-5
323340-01MBL-C
HY-158375MBL-IN-4

Popular Products