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MBL-IN-5

CAT: 0013-GTR19258029-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258029-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL) . It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.
CAS Number
2876921-34-3
Field of Research
Infectious Disease & Virology
Smiles
O=C (O) C=1NC=2C=3C=CC=CC3CCC2C1C=4C=C (Cl) C=CC4OC
Molecular Formula
C20H16ClNO3
Molecular Weight
353.80
Storage Conditions
-20°C
Notes
For research use only.

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