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HEAL-116

CAT: 0013-GTR19272925-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19272925-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HEAL-116 is a potent, specific, and orally active inhibitor of the type 1 3β-hydroxysteroid dehydrogenase (3βHSD1), with an IC50 value of 1.18 μM and a KD value of 1.32 μM. It inhibits both the metabolism of DHEA and DHEA-induced expression of target genes as well as cell proliferation. HEAL-116 is applicable in cancer research, including studies on prostate cancer.
CAS Number
3059767-85-7
Smiles
O=C1C (=COC2=CC (O) =CC=C12) C=3C=CC (Cl) =C (C3) CN4CCOCC4
Molecular Formula
C20H18ClNO4
Molecular Weight
371.82
Storage Conditions
-20°C
Notes
For research use only.

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