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CYC-116

CAT: 0013-GTR19169910-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169910-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYC116 is a potent, selective dual Aurora A/B kinase inhibitor (Ki = 8.0/9.2 nM) with weaker activity against VEGFR2 and minimal off-target effects on other key kinases. It has been utilized in preclinical research to investigate cell cycle disruption and antitumor efficacy in both cellular and animal models.
CAS Number
693228-63-6
Product Name Alternative
AuroraKinase, Aurora Kinase, Aurora B, Aurora A, CYC 116, CYC116, CYC-116, CDK2/CyclinE, CDK9/CyclinT, p70 S6K, Inhibitor, inhibit, FLT3, S6Kinase, S6 Kinase, VEGFR2
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
96.60% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:13.4 mg/mL (36.37 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1nc (N) sc1-c1ccnc (Nc2ccc (cc2) N2CCOCC2) n1
Molecular Formula
C18H20N6OS
Molecular Weight
368.46
Storage Conditions
-20°C
Notes
For research use only.

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