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Antitrypanosomal agent 27

CAT: 0013-GTR19273822-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273822-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitrypanosomal agent 27 (Compound 5c) is a quinazoline derivative with antitrypanosomal activity. It inhibits Trypanosoma brucei (T.b. brucei) with a GI50 value of 31 nM. The compound exhibits a selectivity index of ≥50 towards human liver cancer HepG2 cells and demonstrates no significant cytotoxicity. Antitrypanosomal agent 27 is applicable in the study of human African trypanosomiasis.
CAS Number
2148927-96-0
Smiles
N1=CN=C (NC2=NC=CO2) C3=CC (=CC=C13) C=4C=CC=C (C4) N5CCOCC5
Molecular Formula
C21H19N5O2
Molecular Weight
373.42
Storage Conditions
-20°C
Notes
For research use only.

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