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Debio 1453

CAT: 0013-GTR19273625-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273625-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Debio 1453 is a potent bactericidal FabI inhibitor that is effective against Neisseria gonorrhoeae (IC50 = 0.6 nM) as well as its resistant strains. By inhibiting FabI and binding the non-mutatable NADH cofactor, Debio 1453 demonstrates a low propensity for resistance selection and effectively targets both planktonic and intracellular bacteria. It is capable of eradicating resistant Neisseria gonorrhoeae infections in a mouse vaginal infection model. Debio 1453 can be utilized in gonorrhea-related research.
CAS Number
2422053-29-8
Smiles
CC=1C=2C (OC1CN (C (/C=C/C=3C=C4C (NC3) =NC (=O) [C@@H] (O) [C@@H] (C) N4) =O) C) =CC=CC2
Molecular Formula
C23H24N4O4
Molecular Weight
420.47
Storage Conditions
-20°C
Notes
For research use only.

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