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(Rac) -EBET-1055

CAT: 0013-GTR19268460-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19268460-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R, R) -VRT-534 is the enantiomer of VRT-534. EBET-1055 is a bromodomain and extra-terminal (BET) PROTAC degrader. It effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC) . Additionally, EBET-1055 modulates cancer-associated fibroblast (CAF) activity, increasing the activity of all reporter genes in organoid co-cultures.
CAS Number
3031540-65-2
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1C=2C=CC=C (OCC (=O) N3CCN (CC3) CC4CCN (C=5N=C6C=CC (=CC6=C (N5) C (OC7CC7) (C=8C=CC=CC8) CO) C=9C=C (C (=O) N (C9) C) C) CC4) C2C (=O) N1C%10C (=O) NC (=O) CC%10
Molecular Formula
C51H54N8O9
Molecular Weight
923.02
Storage Conditions
-20°C
Notes
For research use only.

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