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MAO-B-IN-46

CAT: 0013-GTR19265024-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265024-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAO-B-IN-46 (Compound 16) is a selective human MAO-B inhibitor with an IC50 of 26.8 nM, while showing weaker activity against hMAO-A (IC50: 7.2054 μM) . This compound, also referred to as MAO-B-IN-46 (Compound 8), acts as an α-amylase inhibitor with an IC50 of 19.46 μM. It demonstrates certain neuroprotective properties and exhibits no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS radicals, with IC50 values of 17.86 and 17.71 μM, respectively. MAO-B-IN-46 is applicable in research on neurodegenerative diseases like Parkinson's, diabetes, and conditions related to oxidative stress.
CAS Number
27052-20-6
Field of Research
Metabolism Research, Neuroscience
Smiles
O=C (C=1OC=2C=CC=CC2C1) C3=CC=C (Cl) C=C3
Molecular Formula
C15H9ClO2
Molecular Weight
256.68
Storage Conditions
-20°C
Notes
For research use only.

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