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TPP-IOA

CAT: 0013-GTR19264471-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264471-01Size:10 mg
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Description
TPP-IOA is a cytochrome c peroxidase inhibitor. It prevents apoptosis by blocking cardiolipin oxidation and the release of cytochrome c into the cytosol. TPP-IOA interferes with oxidative phosphorylation in isolated mitochondria. It inhibits cell death of SH-SY5Y cells in glucose medium but is ineffective in galactose medium. Additionally, TPP-IOA induces mitochondrial depolarization and network fragmentation, and it reduces radiation-induced mortality in mice.
CAS Number
1423018-61-4
Field of Research
Cell Biology, Metabolism Research
Smiles
[P+] (CCCOC (CCCCCCC/C=C\C[C@H] (CCCCCC) N1C=CN=C1) =O) (C2=CC=CC=C2) (C3=CC=CC=C3) C4=CC=CC=C4.[Br-]
Molecular Formula
C42H56BrN2O2P
Molecular Weight
731.78
Storage Conditions
-20°C
Notes
For research use only.

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