TPMP-I-2

• Description :

  TPMP-I-2 is an anticancer agent that induces cancer cell lines Apoptosis and decreases protein levels of stearoyl-CoA desaturase. TPMP-I-2 prolongs the survival time of nude rats in a simulated micrometastatic cervical cancer model and reduces tumor growth in a breast cancer model in nude mice combined with immunotoxins[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Stearoyl-CoA Desaturase (SCD)

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tpmp-i-2.html

• Smiles :

  O=P(OC)(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)OC

• Molecular Formula :

  C21H21O3P

• Molecular Weight :

  352.36

• References & Citations :

  [1]Risberg K, et al. Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins. J Immunother. 2011 Jun;34 (5) :438-47.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [102660-13-9]