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Nav1.8-IN-20

CAT: 0013-GTR19263260-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263260-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav1.8-IN-20 (Compound I) is an orally active inhibitor of the voltage-gated sodium channel Nav1.8, with an IC50 value of 14 nM. It effectively blocks the generation and propagation of action potentials in peripheral nociceptive neurons, providing analgesic effects. Nav1.8-IN-20 shows potential for research in several pain types, including acute, chronic, inflammatory, and neuropathic pain.
CAS Number
3024470-62-7
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NC1=CN=CN (=O) =C1) C2=CC (Cl) =C (Cl) C=C2OC3=CC=C (OC (F) (F) F) C=C3
Molecular Formula
C18H10Cl2F3N3O4
Molecular Weight
460.19
Storage Conditions
-20°C
Notes
For research use only.

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