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FGFR-IN-14

CAT: 0013-GTR19262842-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262842-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR-IN-14 (compound 10h) is a pan-FGFR inhibitor. It effectively inhibits FGFR1, FGFR2, FGFR3, and the FGFR2V564F gatekeeper mutant, with IC50 values of 46, 41, 99, and 62 nM, respectively. Additionally, FGFR-IN-14 demonstrates strong antiproliferative effects on NCI-H520 lung cancer cells and SNU-16 and KATO III gastric cancer cells, with IC50 values of 19, 59, and 73 nM, respectively.
Field of Research
Cardiovascular Research, Signal Transduction
Molecular Formula
C24H19F2N7O2
Storage Conditions
-20°C
Notes
For research use only.

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