AS-136A

• UNSPSC Description:

  AS-136A is an orally active non-nucleoside inhibitor of the measles virus RNA-dependent RNA polymerase (RdRp) with an IC50 of 2 µM for measles virus[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/as-136a.html

• Smiles:

  O=C(C1=CC(C(F)(F)F)=NN1C)NC2=CC=C(S(=O)(N3CCCCC3)=O)C=C2

• Molecular Weight:

  416.42

• References & Citations:

  [1]Ndungu JM, et al. Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics. J Med Chem. 2012;55(9):4220-4230.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  949898-66-2