BG-136

• Description:

  BG-136 is an innate immune stimulant isolated from Durvillaea Antarctica that can simultaneously stimulate the activation of both innate and adaptive immune cells in the tumor microenvironment (TME), exerting a broad-spectrum antitumor effect[1].

• UNSPSC:

  12352211

• Target:

  Arginase; CD74; IFNAR; NO Synthase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bg-136.html

• Smiles:

  [BG-136]

• Molecular Weight:

  4000-7000

• References & Citations:

  [1]Song Q, et al. A β-1, 3/1, 6-glucan enhances anti-tumor effects of PD1 antibody by reprogramming tumor microenvironment[J]. International Journal of Biological Macromolecules, 2024, 279: 134660.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 1