BG-136

• Description :

  BG-136 is an innate immune stimulant isolated from Durvillaea Antarctica that can simultaneously stimulate the activation of both innate and adaptive immune cells in the tumor microenvironment (TME), exerting a broad-spectrum antitumor effect[1].

• UNSPSC :

  12352211

• Target :

  Arginase; CD74; IFNAR; NO Synthase

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bg-136.html

• Smiles :

  [BG-136]

• Molecular Weight :

  4000-7000

• References & Citations :

  [1]Song Q, et al. A β-1, 3/1, 6-glucan enhances anti-tumor effects of PD1 antibody by reprogramming tumor microenvironment[J]. International Journal of Biological Macromolecules, 2024, 279: 134660.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 1