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AurkA allosteric-IN-1

CAT: 0013-GTR19262122-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262122-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor with an IC50 of 6.50 μM, which inhibits both the catalytic and non-catalytic activities of Aurora A. Aurora A is involved in the regulation of bipolar mitotic spindle assembly and the fidelity of chromosome segregation during mitosis. AurkA allosteric-IN-1 interferes with Aurora A by binding to the Y-pocket, thereby preventing its interaction with the activator TPX2.
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Molecular Formula
C20H16N2O3
Storage Conditions
-20°C
Notes
For research use only.

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