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Anti-inflammatory agent 68

CAT: 0013-GTR19261792-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261792-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-inflammatory agent 68 (compound 7b) is a dual inhibitor that targets Carbonic Anhydrase and COX-2, and is a sulfonamide derivative of Polmacoxib, exhibiting anti-inflammatory and analgesic properties. The IC50 values of Anti-inflammatory agent 68 for COX-1 and COX-2 are 12.6 μM and 60 nM, respectively. It binds to different Carbonic Anhydrase isoforms with Ki values of 52.6 nM (CA I), 79.1 nM (CA II), 58.1 nM (CA IX), and 17.2 nM (CA XII) .
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience
Molecular Formula
C12H13N3O6S2
Storage Conditions
-20°C
Notes
For research use only.

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