Products for Research Use Only
RegisterLogin

(+) -AJ-76

CAT: 0013-GTR19264839-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19264839-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(+) -AJ-76 is an antagonist of the dopamine autoreceptor, with a weak antagonistic effect on postsynaptic dopamine receptors. (+) -AJ 76 HCl can increase the synthesis and turnover of dopamine in the rat brain, and can also antagonize the sedative effect of low-dose apomorphine.
CAS Number
85379-09-5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.02% (May vary between batches)
Smiles
O (C) C1=C2C ([C@H] (C) [C@H] (NCCC) CC2) =CC=C1
Molecular Formula
C15H23NO
Molecular Weight
233.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

AJ 76

(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin is a secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively). It has a role as a dopaminergic antagonist. It is a member of tetralins and a secondary amino compound. It is a conjugate base of a (1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+). It derives from a hydride of a tetralin.

CAS Number85379-09-5
PubChem CID122334
IUPAC Name(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
Molecular FormulaC15H23NO
Molecular Weight233.35
XLogP3.4
Topological Polar Surface Area21.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Heavy Atom Count17
Formal Charge0
Complexity231
SMILES
CCCN[C@@H]1CCC2=C([C@@H]1C)C=CC=C2OC
InChI
InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
InChIKey
YGHLYBIUVOLKCV-SMDDNHRTSA-N
Chemical Structure
2D Structure
2D structure of AJ 76
CAS: 85379-09-5
CID: 122334
Formula: C15H23NO
MW: 233.35
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight233.35
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass233.177964357
Monoisotopic Mass233.177964357
Topological Polar Surface Area21.3 Ų
Heavy Atom Count17
Formal Charge0
Complexity231
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19209387-01AJ-3941
GTR19209347-01AJ-108235
GTR19183088Taccalonolide AJ
GTR19220601-01EGFR-IN-76
GTR19241167-01α-Glucosidase-IN-76
GTR19239272-01HDAC-IN-76
GTR19238578-01AChE-IN-76
GTR19238286-01RO-76
GTR19063674-01E-76
GTR19235159-01HSD17B13-IN-76

Alternative Products

CatalogName
HY-111283AJ-76
B6403-10(+)-AJ 76 hydrochloride
441083-01(+) -AJ 76 Hydrochloride
T84695-01AJ-76 hydrochloride
HY-101065-01AJ-76 (hydrochloride)
M31439-01Taccalonolide AJ
T70682-01AJ-3941
MBS5813876AJ-108235
S-1207Dibenz(aj)acridine - 1ML
076808Mouse AJ Spare Parts and Accessories

Popular Products