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Rtioxa-43

CAT: 0013-GTR19259465Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259465Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RTIOXA-43 is a dual orexin receptor agonist exhibiting potent activity at both OX1 and OX2 receptors, with EC50 values of 24 nM for each . In vivo studies involving 12-month-old mice have demonstrated that peripheral administration of RTIOXA-43 significantly increases wakefulness, reduces total sleep time, and enhances sleep/wake consolidation by decreasing the number of sleep episodes and extending their duration . These findings suggest that RTIOXA-43 holds promise as a therapeutic candidate for treating orexin-deficient conditions such as narcolepsy.​
CAS Number
2832067-72-6
Purity
0.98
Smiles
S (C1C (=CC=C (C=1) C1C=CC=C (C (N (C) CC2C=CN=CC=2) =O) C=1) OC) (NC1C=CC=C (C=1) NCCNC (C1C=CC=C (C) C=1) =O) (=O) =O
Molecular Formula
C37H37N5O5S
Molecular Weight
663.785187482834
Notes
For research use only.

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